The Dimitrova lab focuses on long non-coding RNAs (lncRNAs) and their roles in the regulation of critical cellular pathways during tumor development. Using advanced genomic, genetic and molecular biology tools, we study the contribution of lncRNAs to cancer-relevant processes at the cellular and organismal level. Our aim is to dissect the complex biology of this novel class of RNAs and to gain a deeper understanding of the contribution of lncRNAs in health and disease.